Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450975 | 0.91 | FOLH1 (0.54) | FOLH1PPARAPPARGMMESLC1A1 | |
| SCHEMBL5347315 | 0.91 | FOLH1 (0.54) | FOLH1PPARAPPARGMMESLC1A1 | |
| SCHEMBL2026078 | 0.89 | FOLH1 (0.50) | FOLH1PPARAPPARGMMESLC1A1 | |
| SCHEMBL2026077 | 0.89 | FOLH1 (0.50) | FOLH1PPARAPPARGMMESLC1A1 | |
| SCHEMBL6446640 | 0.88 | FOLH1 (0.49) | FOLH1PPARAPPARGMMESLC1A1 | |
| SCHEMBL6446635 | 0.88 | FOLH1 (0.49) | FOLH1PPARAPPARGMMESLC1A1 | |
| Hydrochloric Acid SCHEMBL20996763 | 0.87 | FOLH1 (0.57) | FOLH1PPARAPPARGMMESLC1A1 | |
| SCHEMBL6311567 | 0.87 | PPARA (0.53) | FOLH1PPARAPPARGMMESLC1A1 | |
| SCHEMBL9450999 | 0.86 | FOLH1 (0.50) | FOLH1PPARAPPARGMMESLC1A1 | |
| SCHEMBL9451004 | 0.84 | GGT1 (0.49) | FOLH1PPARAPPARGMMECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061957-B1 | MANGANESE (II) CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-10-30 | — | — | EP | disclosed |
| US-5182370-A | Diagnostic NMR imaging | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1993-01-26 | — | — | US | disclosed |
| US-4980502-A | For nuclear magnetic resonance imaging | BRACCO INDUSTRIA CHIMICA, S.P.A. (IT) | 1990-12-25 | — | — | US | disclosed |
| EP-0230893-B1 | PARAMAGNETIC CHELATES | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1990-06-13 | — | — | EP | disclosed |
| US-4916246-A | Paramagnetic chelates useful for NMR imaging | BRACCO CHIMICA S.P.A. (IT) | 1990-04-10 | — | — | US | disclosed |
| EP-0230893-A2 | Paramagnetic chelates | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1987-08-05 | — | — | EP | disclosed |