Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Chloropyridine SCHEMBL9483222 | 0.95 | TDP1 (0.55) | TDP1ALDH1A1FKBP5CCR1CCR5 | |
| Dipyridyl SCHEMBL7143241 | 0.80 | KDM4E (0.58) | TDP1ALDH1A1FKBP5CCR1CCR5 | |
| Dipyridyl SCHEMBL28370248 | 0.80 | KDM4E (0.58) | TDP1ALDH1A1FKBP5CCR1CCR5 | |
| 1,2-Dichlorobenzene SCHEMBL27574752 | 0.79 | ALDH1A1 (0.59) | TDP1ALDH1A1FKBP5KDM4ELMNA | |
| 2-Chloropyridine SCHEMBL5838075 | 0.79 | TDP1 (0.73) | TDP1CCR1CCR5CCR8KDM4E | |
| Dipyridyl SCHEMBL5691657 | 0.79 | KDM4E (0.52) | TDP1ALDH1A1FKBP5CCR1CCR5 | |
| Dipyridyl SCHEMBL5456778 | 0.79 | KDM4E (0.52) | TDP1ALDH1A1FKBP5CCR1CCR5 | |
| Dipyridyl SCHEMBL9943536 | 0.79 | KDM4E (0.52) | TDP1ALDH1A1FKBP5CCR1CCR5 | |
| Dipyridyl SCHEMBL3847534 | 0.78 | KDM4E (0.56) | TDP1ALDH1A1FKBP5CCR1CCR5 | |
| Dipyridyl SCHEMBL3491432 | 0.78 | KDM4E (0.56) | TDP1ALDH1A1FKBP5CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506251-A1 | SILICONE COMPOSITION WHICH CAN BE CROSSLINKED INTO AN ELASTOMER BY HYDROSILYLATION IN THE PRESENCE OF CARBENE-BASED METAL CATALYSTS, AND CATALYSTS OF THIS TYPE | Rhodia Chimie (FR) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003099909-A1 | SILICONE COMPOSITION WHICH CAN BE CROSSLINKED INTO AN ELASTOMER BY HYDROSILYLATION IN THE PRESENCE OF CARBENE-BASED METAL CATALYSTS, AND CATALYSTS OF THIS TYPE | RHODIA CHIMIE (FR) | 2003-12-04 | — | — | WO | disclosed |