Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456741 | 0.91 | PIN1 (0.39) | MAP4K4ALDH1A1HPGDTSHRSYK | |
| SCHEMBL7769098 | 0.86 | EZH2 (0.35) | HIF1AMAP4K4ALDH1A1HPGDTSHR | |
| SCHEMBL9494059 | 0.86 | MAP4K4 (0.41) | MAP4K4ALDH1A1HPGDTSHRSYK | |
| SCHEMBL22371494 | 0.84 | MAP4K4 (0.40) | MAP4K4ALDH1A1HPGDTSHRSYK | |
| SCHEMBL9065463 | 0.83 | MAP4K4 (0.39) | MAP4K4ALDH1A1HPGDTSHRSYK | |
| SCHEMBL55086 | 0.83 | MAP4K4 (0.39) | MAP4K4ALDH1A1HPGDTSHRSYK | |
| SCHEMBL21389595 | 0.82 | MAP4K4 (0.39) | MAP4K4ALDH1A1HPGDTSHRSYK | |
| SCHEMBL10045475 | 0.82 | MAP4K4 (0.39) | MAP4K4ALDH1A1HPGDTSHRSYK | |
| Azoxystrobin SCHEMBL3785319 | 0.82 | HIF1A (0.43) | HIF1AALDH1A1 | |
| Azoxystrobin SCHEMBL4113006 | 0.81 | MAP4K4 (0.38) | MAP4K4ALDH1A1HPGDTSHRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239805-A1 | Mixtures of fused pyrimidinones and dinitrophenolic compounds useful for controlling powdery mildews | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239805-A1 | Mixtures of fused pyrimidinones and dinitrophenolic compounds useful for controlling powdery mildews | CBR3, CBR1, C9 | HIF1A 4549/4885MAP4K4 3478/4885ALDH1A1 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.