SCHEMBL64475

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12024471	0.83	PLK1 (0.56)	POLBSMN1; SMN2GAANPC1CYP3A4
	SCHEMBL343830	0.81	POLB (0.65)	POLBPRSS1CTSGCTRB1CMA1
	SCHEMBL12024336	0.79	POLB (0.62)	POLBPRSS1CTSGCTRB1CMA1
	SCHEMBL12024482	0.79	NPC1 (0.55)	SMN1; SMN2GAANPC1RAB9ACES2
	SCHEMBL18059036	0.78	SMN1; SMN2 (0.49)	POLBSMN1; SMN2GAANPC1RAB9A
	SCHEMBL4516395	0.78	POLB (0.71)	POLBPRSS1CTSGCTRB1CMA1
	SCHEMBL408310	0.77	CYP2C9 (0.67)	POLBPRSS1CTSGCTRB1CMA1
	SCHEMBL24263392	0.76	POLB (1.00)	POLBPRSS1CTSGCTRB1CMA1
	SCHEMBL12833048	0.76	POLB (0.73)	POLBPRSS1CTSGCTRB1CMA1
	SCHEMBL12024474	0.76	POLB (0.54)	POLBSMN1; SMN2GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.