Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12024336 | 0.86 | POLB (0.62) | POLBCYP2C9SMN1; SMN2EPHX1HDAC3 | |
| SCHEMBL24534686 | 0.84 | HDAC1 (0.60) | POLBSMN1; SMN2HDAC3HDAC1HDAC8 | |
| SCHEMBL12302098 | 0.84 | ALDH1A1 (0.55) | POLBSMN1; SMN2HDAC1HDAC6GAA | |
| SCHEMBL408310 | 0.83 | CYP2C9 (0.67) | POLBCYP2C9SMN1; SMN2EPHX1HDAC3 | |
| SCHEMBL16776702 | 0.82 | OGG1 (0.50) | POLBSMN1; SMN2HDAC3CA12HDAC1 | |
| SCHEMBL3755534 | 0.82 | POLB (0.56) | POLBSMN1; SMN2ALOX15KDM4ENPC1 | |
| SCHEMBL22987120 | 0.82 | MAPT (0.49) | POLBCYP2C9SMN1; SMN2HDAC1KDM4E | |
| SCHEMBL1742088 | 0.82 | EGLN1 (0.50) | POLBKDM4EGAANPC1RAB9A | |
| SCHEMBL9828913 | 0.82 | SMN1; SMN2 (0.60) | POLBSMN1; SMN2HDAC8HDAC6NPC1 | |
| SCHEMBL10504078 | 0.82 | POLB (0.58) | POLBCYP2C9SMN1; SMN2EPHX1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140080788-A1 | NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2014-03-20 | — | — | US | claimed |
| EP-2673260-A1 | GLUCAGON RECEPTOR MODULATOR | Pfizer Inc (US) | 2013-12-18 | — | — | EP | claimed |
| WO-2012107850-A1 | GLUCAGON RECEPTOR MODULATOR | PFIZER INC. (US) | 2012-08-16 | — | — | WO | claimed |
| US-4213784-A | Process for producing heat developable light-sensitive compositions and elements | FUJI PHOTO FILM CO., LTD. (JP) | 1980-07-22 | — | — | US | claimed |
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| CN-116925066-A | Indole thiazole ketone compound and application thereof | 张所明 | 2023-10-24 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-111196772-B | Aroylamino isobutyryl derivative and application thereof | 沈阳化工研究院有限公司 | 2022-09-30 | — | — | CN | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
| CN-111196772-A | Aroylamino isobutyryl derivative and application thereof | 沈阳化工研究院有限公司 | 2020-05-26 | — | — | CN | disclosed |
| WO-2009127722-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |
| CN-1356977-A | Glucagon antagonists/inverse agonists | NOVO NORDISK AS (DK) | 2002-07-03 | — | — | CN | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| EP-0014437-B1 | NOVEL 1-ARYL-2-ACYLAMIDO-3-FLUORO-1-PROPANOLS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1983-02-23 | — | — | EP | disclosed |
| US-4213784-A | Process for producing heat developable light-sensitive compositions and elements | FUJI PHOTO FILM CO., LTD. (JP) | 1980-07-22 | — | — | US | disclosed |
| EP-0001864-A1 | Novel 6-oxygenated-3,20-dioxo-pregnane derivatives, process for the preparation thereof, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | POLB 3788/4885CYP2C9 1658/4885SMN1; SMN2 13/4885 |
| US-20140080788-A1 | NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS | GRK5, GPBAR1, GPR55 | POLB 3238/4885CYP2C9 1392/4885SMN1; SMN2 3874/4885 |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | POLB 3788/4885CYP2C9 1658/4885SMN1; SMN2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.