Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL2310518 | 0.98 | CYP2C9 (0.65) | CYP2C9SMN1; SMN2EPHX1POLBHDAC3 | |
| Hydrochloric Acid SCHEMBL22076570 | 0.98 | CYP2C9 (0.65) | CYP2C9SMN1; SMN2EPHX1POLBHDAC3 | |
| SCHEMBL29201540 | 0.98 | CYP2C9 (0.65) | CYP2C9SMN1; SMN2EPHX1POLBHDAC3 | |
| Bromide SCHEMBL6851253 | 0.98 | CYP2C9 (0.65) | CYP2C9SMN1; SMN2EPHX1POLBHDAC3 | |
| Thiosulfuric Acid SCHEMBL11090482 | 0.89 | CYP2C9 (0.56) | CYP2C9SMN1; SMN2EPHX1POLBHDAC3 | |
| Thiosulfuric Acid SCHEMBL11090486 | 0.89 | EPHX1 (0.60) | CYP2C9SMN1; SMN2EPHX1POLBHDAC3 | |
| SCHEMBL17865779 | 0.88 | LMNA (0.58) | CYP2C9SMN1; SMN2EPHX1POLBHDAC1 | |
| SCHEMBL6416083 | 0.88 | NPC1 (0.60) | CYP2C9SMN1; SMN2EPHX1POLBGAA | |
| SCHEMBL15946358 | 0.87 | CACNA1B (0.67) | SMN1; SMN2POLBLMNAHTTNPC1 | |
| SCHEMBL21249304 | 0.84 | LMNA (0.58) | CYP2C9SMN1; SMN2HDAC8HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504626-A | Preparation method of diethyl hexyl butyryl amino triazinone | 湖北汇达科技发展有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-111100080-B | Preparation method of letrozole | 南京亿华药业有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-111699250-A | Carboxyesterase polypeptides for amide coupling | 科德克希思公司 | 2020-09-22 | — | — | CN | claimed |
| US-20190177707-A1 | CARBOXYESTERASE POLYPEPTIDES FOR AMIDE COUPLING | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2019-06-13 | — | — | US | claimed |
| CN-104447391-B | A kind of preparation method of di-2-ethylhexylphosphine oxide amide derivatives | 苏州波菲特新材料科技有限公司 | 2016-07-06 | — | — | CN | claimed |
| CN-104447391-A | Methylenebisamide derivative and preparation method thereof | SUZHOU PERFECT NEW MATERIAL TECHNOLOGY CO LTD | 2015-03-25 | — | — | CN | claimed |
| EP-2844637-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | PharmAxis Ltd (AU) | 2015-03-11 | — | — | EP | claimed |
| WO-2013163675-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | PHARMAXIS LTD. (AU) | 2013-11-07 | — | — | WO | claimed |
| EP-2639237-A1 | A process for the manufacture of optically active phosphinamide | Centrum Badan Molekularnych I Makromolekularnych Pan (PL) | 2013-09-18 | — | — | EP | claimed |
| US-20100197954-A1 | SYNTHESIS OF SPHINGOSINES AND THEIR DERIVATIVES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-08-05 | — | — | US | claimed |
| WO-2008030840-A2 | SYNTHESIS OF SPHINGOSINES AND THEIR DERIVATIVES | EMORY UNIVERSITY (US) | 2008-03-13 | — | — | WO | claimed |
| EP-1836174-A2 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC. (US) | 2007-09-26 | — | — | EP | claimed |
| WO-2006039718-A2 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2006-04-13 | — | — | WO | claimed |
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | claimed |
| EP-0755250-A4 | BENZAMIDE-CONTAINING PHARMACEUTICAL COMPOSITIONS | CENTAUR PHARMACEUTICALS INC (US) | 2000-04-19 | — | — | EP | claimed |
| EP-0755250-A1 | BENZAMIDE-CONTAINING PHARMACEUTICAL COMPOSITIONS | CENTAUR PHARMACEUTICALS, INC. (US) | 1997-01-29 | — | — | EP | claimed |
| US-5472983-A | Neurodegenerative conditions associated with dopamine depletion, e.g. Alzheimer's, Parkinson's, multiple sclerosis, Huntington's amyltrophic lateral sclerosis and vision defects | CENTAUR PHARMACEUTICALS, INC. (US) | 1995-12-05 | — | — | US | claimed |
| WO-1995028153-A1 | BENZAMIDE-CONTAINING PHARMACEUTICAL COMPOSITIONS | CENTAUR PHARMACEUTICALS, INC. (US) | 1995-10-26 | — | — | WO | claimed |
| US-12286653-B2 | Carboxyesterase polypeptides for amide coupling | CODEXIS, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| US-3883590-A | Preparation of n-alkylarylcarboxamides | UNIVERSAL OIL PROD CO | 1975-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197954-A1 | SYNTHESIS OF SPHINGOSINES AND THEIR DERIVATIVES | SPHK1, SPHK2, S1PR2 | CYP2C9 4869/4885SMN1; SMN2 999/4885EPHX1 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.