Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 5/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026383 | 0.80 | ITGB3 (0.43) | WDR5CXCR4ITGB3ITGAVKDM4E | |
| SCHEMBL6440900 | 0.78 | ITGB3 (0.49) | ITGB3ITGAVKDM4EKMT2AMEN1 | |
| SCHEMBL5028393 | 0.71 | ITGB3 (0.52) | CXCR4ITGB3ITGAVKMT2A | |
| SCHEMBL6440635 | 0.67 | ITGB3 (0.55) | ITGB3ITGAVTSHR | |
| SCHEMBL6424594 | 0.67 | ITGB3 (0.51) | ITGB3ITGAVMAPT | |
| SCHEMBL661911 | 0.66 | WDR5 (0.37) | WDR5ITGB3ITGAVALDH1A1MAPT | |
| SCHEMBL662079 | 0.62 | TP53 (0.51) | KDM4ELMNAALDH1A1MAPTTSHR | |
| SCHEMBL662880 | 0.61 | MAPT (0.54) | KDM4ELMNAALDH1A1MAPTTSHR | |
| SCHEMBL30361168 | 0.61 | MAPT (0.54) | KDM4ELMNAALDH1A1MAPTTSHR | |
| SCHEMBL3372513 | 0.61 | ITGB3 (0.33) | WDR5ITGB3ITGAVALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |