Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273082 | 0.76 | CYP2A6 (0.46) | CYP2A6GPR84PAX8CYP1A2KDM4E | |
| SCHEMBL5852315 | 0.76 | CYP2A6 (0.46) | CYP2A6GPR84PAX8CYP1A2KDM4E | |
| SCHEMBL6057396 | 0.76 | SMN1; SMN2 (0.35) | LMNAKMT2A | |
| SCHEMBL5850883 | 0.74 | CYP2A6 (0.47) | CYP2A6GPR84PAX8CYP1A2KCNH2 | |
| SCHEMBL10938638 | 0.69 | CYP2A6 (0.58) | CYP2A6PAX8CYP1A2KCNH2LMNA | |
| SCHEMBL224341 | 0.69 | CYP2A6 (0.58) | CYP2A6PAX8CYP1A2USP2PAK1 | |
| SCHEMBL5850892 | 0.69 | CYP2A6 (0.44) | CYP2A6GPR84PAX8CYP1A2KCNH2 | |
| SCHEMBL9648939 | 0.67 | CYP2A6 (0.54) | CYP2A6PAX8CYP1A2KCNH2LMNA | |
| SCHEMBL269051 | 0.66 | CYP2A6 (0.48) | CYP2A6PAX8CYP1A2KDM4ELMNA | |
| SCHEMBL7011793 | 0.66 | CYP2A6 (0.48) | CYP2A6GPR84PAX8CYP1A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |