Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850883 | 0.83 | CYP2A6 (0.47) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL5852291 | 0.76 | KMT2A (0.34) | CYP2A6CYP1A2TSHRLMNASMN1; SMN2 | |
| SCHEMBL25273082 | 0.75 | CYP2A6 (0.46) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL5852315 | 0.75 | CYP2A6 (0.46) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL10938638 | 0.74 | CYP2A6 (0.58) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL9648939 | 0.71 | CYP2A6 (0.54) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL269051 | 0.70 | CYP2A6 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL8153278 | 0.69 | CYP2A6 (0.47) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL5673224 | 0.67 | CYP2A6 (0.65) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL7011793 | 0.67 | CYP2A6 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |