Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938638 | 0.83 | CYP2A6 (0.58) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL31005180 | 0.79 | CYP2A6 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL269051 | 0.79 | CYP2A6 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL8153278 | 0.77 | CYP2A6 (0.47) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL10438032 | 0.77 | ALDH1A1 (0.46) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL25273082 | 0.76 | CYP2A6 (0.46) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL5852315 | 0.76 | CYP2A6 (0.46) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL7108615 | 0.75 | CYP2A6 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL7011793 | 0.75 | CYP2A6 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL25385558 | 0.75 | CYP2A6 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118611-A | Useful for diagnostic, imaging treatment of cancer involving antibody binding interaction with marker | ADEZA BIOMEDICAL CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0352722-A2 | Adenocarcinoma antigen binding methods and reagents | Smith, Lloyd H. (US) | 1990-01-31 | — | — | EP | disclosed |