Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448295 | 1.00 | L3MBTL1 (0.40) | L3MBTL1CNR1POLBSMN1; SMN2HPGD | |
| SCHEMBL6448101 | 0.84 | ALDH1A1 (0.40) | L3MBTL1SMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL6448096 | 0.84 | ALDH1A1 (0.40) | L3MBTL1SMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL6450358 | 0.83 | PDK2 (0.40) | L3MBTL1POLBSMN1; SMN2KMT2APDK2 | |
| SCHEMBL6446835 | 0.83 | HCRTR2 (0.39) | POLBSMN1; SMN2HPGDKMT2APDK2 | |
| SCHEMBL6446836 | 0.83 | HCRTR2 (0.39) | POLBSMN1; SMN2HPGDKMT2APDK2 | |
| SCHEMBL6450356 | 0.83 | PDK2 (0.40) | L3MBTL1POLBSMN1; SMN2KMT2APDK2 | |
| SCHEMBL6450053 | 0.79 | L3MBTL1 (0.42) | L3MBTL1POLBSMN1; SMN2HPGDKDM4E | |
| SCHEMBL6450044 | 0.79 | L3MBTL1 (0.42) | L3MBTL1POLBSMN1; SMN2HPGDKDM4E | |
| SCHEMBL6450387 | 0.79 | L3MBTL1 (0.42) | L3MBTL1POLBSMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921832-B2 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2005-07-26 | — | — | US | disclosed |
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1422226-A1 | Optically active fluorine-containing compounds and processes for their production | Tosoh Corporation (JP) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | CYP2C19, CYP2F1, CYP2B6 | L3MBTL1 1711/4885CNR1 3294/4885POLB 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.