Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448582 | 0.91 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL203794 | 0.91 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL29358657 | 0.91 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL17755552 | 0.89 | MEN1 (0.40) | SMN1; SMN2LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL2857206 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL15298018 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL12503892 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL8812803 | 0.86 | KMT2A (0.39) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL9943424 | 0.86 | KMT2A (0.39) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL55086 | 0.84 | MAP4K4 (0.39) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893651-B1 | Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-17 | — | — | US | disclosed |