Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 4/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.50 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004798 | 0.91 | KCNQ2 (0.56) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6389065 | 0.88 | MAPT (0.53) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL8966006 | 0.87 | KCNQ2 (0.58) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL4972519 | 0.84 | KCNQ2 (0.59) | KCNQ2KCNQ3KCNQ4KCNQ5RORC | |
| SCHEMBL6003001 | 0.82 | MAPT (0.51) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6004889 | 0.81 | THRB (0.51) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL6005439 | 0.80 | KCNQ2 (0.64) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6004318 | 0.80 | MAPT (0.46) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6005020 | 0.79 | KCNQ3 (0.52) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL20133927 | 0.79 | THRB (0.53) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606247-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. Lundbeck A/S (DK) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080950-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-23 | — | — | WO | disclosed |