Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.48 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.48 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133927 | 0.93 | THRB (0.53) | THRBKCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL6004798 | 0.89 | KCNQ2 (0.56) | THRBKCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL6004295 | 0.88 | KCNQ3 (0.50) | KCNQ2KCNQ3KCNQ4KCNQ5KMT2A | |
| SCHEMBL6004957 | 0.87 | KCNQ3 (0.55) | KCNQ2KCNQ3KCNQ4KCNQ5KMT2A | |
| SCHEMBL8966006 | 0.87 | KCNQ2 (0.58) | THRBKCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL6004934 | 0.86 | MAPT (0.49) | KCNQ2KCNQ3KCNQ4KCNQ5KMT2A | |
| SCHEMBL6005096 | 0.85 | MAPT (0.48) | KCNQ2KCNQ3KCNQ4KCNQ5KMT2A | |
| SCHEMBL30814183 | 0.84 | KCNQ2 (0.64) | THRBKCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL4983950 | 0.84 | THRB (0.52) | THRBKCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL3106484 | 0.84 | KCNQ2 (0.64) | THRBKCNQ2KCNQ3KCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | H. LUNDBECK A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | CYP3A43, UGT2B7, CYP3A7 | THRB 3021/4885KCNQ2 2612/4885KCNQ3 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.