Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | CHUK | O15111 | 2/20 | 0.53 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM6A | O15550 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452100 | 0.91 | CASP3 (0.51) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL6451920 | 0.88 | CASP3 (0.51) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL6452697 | 0.82 | NPC1 (0.45) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL6454743 | 0.81 | NPC1 (0.56) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL6453920 | 0.80 | GAA (0.52) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL6452338 | 0.79 | MAPT (0.57) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL6449624 | 0.79 | S1PR1 (0.50) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL6452382 | 0.79 | SMN1; SMN2 (0.47) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL6454119 | 0.78 | SMN1; SMN2 (0.58) | MAPTALDH1A1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL6452064 | 0.78 | MAPK1 (0.43) | CASP3SENP8SENP7SENP6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | CASP3 330/4885SENP8 1825/4885SENP7 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.