Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510712 | 0.87 | HDAC4 (0.54) | CYP1A2CYP2C19MEN1KMT2ARAB9A | |
| SCHEMBL1196472 | 0.84 | MAOB (0.56) | MAPTLMNACHRM2MAOB | |
| SCHEMBL8234606 | 0.83 | HTT (0.62) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL30091081 | 0.83 | MEN1 (0.57) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL632217 | 0.82 | CHRM2 (0.55) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6700054 | 0.82 | CHRM2 (0.55) | MEN1KMT2AMAPTALDH1A1CHRM2 | |
| SCHEMBL6493476 | 0.80 | GABRP (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 | |
| SCHEMBL6692696 | 0.80 | FFAR1 (0.67) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6691692 | 0.79 | MAOB (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 | |
| SCHEMBL6695981 | 0.79 | LMNA (0.51) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606247-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. Lundbeck A/S (DK) | 2005-12-21 | — | — | EP | claimed |
| WO-2004080950-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-23 | — | — | WO | claimed |