⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601159 | 0.80 | — | — | |
| SCHEMBL21626847 | 0.74 | ALB (0.31) | — | |
| SCHEMBL27533793 | 0.70 | KMT2A (0.41) | — | |
| SCHEMBL1836382 | 0.69 | DNMT1 (0.41) | — | |
| SCHEMBL2221563 | 0.66 | ALB (0.39) | — | |
| SCHEMBL21130861 | 0.61 | ADK (0.45) | — | |
| SCHEMBL4590964 | 0.61 | ALB (0.46) | — | |
| SCHEMBL9856409 | 0.61 | LMNA (0.62) | — | |
| SCHEMBL9856439 | 0.61 | LMNA (0.62) | — | |
| SCHEMBL27798766 | 0.60 | ALB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957926-B1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS FOR THE MODULATION OF THE EXPRESSION OF B7 PROTEIN | ISIS PHARMACEUTICALS INC (US) | 2005-02-16 | — | — | EP | claimed |
| CN-107385050-A | For detecting the gene marker, kit and cancer of pancreas detection method of cancer of pancreas | 上海易毕恩生物技术有限公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-107385051-A | For detecting liver tumour good pernicious gene marker, kit and detection method | 上海易毕恩生物技术有限公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-107365845-A | For detecting the gene marker, kit and lung cancer detection method of lung cancer | 上海易毕恩生物技术有限公司 | 2017-11-21 | — | — | CN | disclosed |