Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618956 | 0.85 | ADORA2A (0.35) | KMT2AMEN1MAPTSTAT3RAB9A | |
| SCHEMBL18610783 | 0.78 | MAT2A (0.33) | HSD17B10ADORA2ACYP3A4CYP2C19 | |
| SCHEMBL2463445 | 0.71 | APP (0.56) | KMT2AMAPTADORA2A | |
| SCHEMBL17077972 | 0.70 | GRIA1 (0.33) | — | |
| SCHEMBL2221557 | 0.69 | ADORA3 (0.41) | KMT2AMEN1MAPTRAB9AHSD17B10 | |
| SCHEMBL26506 | 0.68 | SUMO1 (0.36) | — | |
| SCHEMBL546483 | 0.68 | GRIA1 (0.32) | — | |
| SCHEMBL2512344 | 0.68 | SUMO1 (0.36) | — | |
| SCHEMBL2463433 | 0.67 | KMT2A (0.57) | KMT2AMEN1MAPTRAB9AHSD17B10 | |
| SCHEMBL1836384 | 0.67 | KDR (0.36) | MAPTHSD17B10CYP2C19CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957926-B1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS FOR THE MODULATION OF THE EXPRESSION OF B7 PROTEIN | ISIS PHARMACEUTICALS INC (US) | 2005-02-16 | — | — | EP | claimed |