Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12284725 | 0.90 | THRB (0.30) | THRB | |
| SCHEMBL22040828 | 0.85 | — | — | |
| SCHEMBL24179933 | 0.84 | TSHR (0.31) | TSHR | |
| SCHEMBL8125829 | 0.84 | POLB (0.39) | POLBGAANPSR1ALDH1A1TP53 | |
| SCHEMBL19263775 | 0.84 | THRB (0.30) | THRB | |
| SCHEMBL36866 | 0.83 | POLB (0.41) | POLBGAANPSR1ALDH1A1TSHR | |
| SCHEMBL17445920 | 0.81 | ALDH1A1 (0.32) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL1341185 | 0.81 | TSHR (0.55) | POLBGAANPSR1ALDH1A1TP53 | |
| SCHEMBL4608266 | 0.79 | TSHR (0.44) | POLBGAANPSR1ALDH1A1TP53 | |
| SCHEMBL10056774 | 0.79 | THRB (0.38) | ALDH1A1TP53TSHRHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113543-A1 | Alpha, omega-allyl terminated linear poly(methacrylic acid) macromonomers for end-linked hydrogels and method of preparation | MORNINGSIDE, COLUMBIA UNIVERSITY OF NY | 2005-05-26 | — | — | US | disclosed |
| WO-2003101934-A1 | α,φ-ALLYL TERMINATED LINEAR POLY(METHACRYLIC ACID) MACROMONOMERS FOR END-LINKED HYDROGELS AND METHOD OF PREPARATION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-12-11 | — | — | WO | disclosed |