SCHEMBL8548443

SCHEMBL8548443

C=CCC(CC(O)C(N)=O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 13/20 0.61
GRIK2 Q13002 13/20 0.61
CPA1 P15085 1/20 0.46
CYP2C19 P33261 1/20 0.34
SLC1A1 P43005 2/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
GRIK3 Q13003 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6050002 0.83 GRIK1 (0.75) GRIK1GRIK2CPA1CYP2C19SLC1A1
SCHEMBL6449828 0.77
SCHEMBL891727 0.76 GRIK1 (0.64) GRIK1GRIK2CPA1CYP2C19
SCHEMBL15312401 0.76 GRIK1 (1.00) GRIK1GRIK2SLC1A1SLC1A3SLC1A2
SCHEMBL7751545 0.76 GRIK1 (1.00) GRIK1GRIK2SLC1A1SLC1A3SLC1A2
SCHEMBL594101 0.76 GRIK1 (1.00) GRIK1GRIK2SLC1A1SLC1A3SLC1A2
SCHEMBL594100 0.76 GRIK1 (1.00) GRIK1GRIK2SLC1A1SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL9087042 0.74 GRIK1 (0.96) GRIK1GRIK2SLC1A1SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL9087046 0.74 GRIK1 (0.96) GRIK1GRIK2SLC1A1SLC1A3SLC1A2
SCHEMBL174976 0.74 GRIK1 (0.50) GRIK1GRIK2CPA1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990166-A O-(1-CARBOXYOCTYLCARBONYLAMINO)PHENOL AS A CARRIER; DRUG DELIVERY; ACID RESISTANCE; FORMING NONCOVALENT MIXTURES WITH BIOLOGICALLY ACTIVE AGENTS FOR ORAL ADMINISTRATION; E.G., CALCITONIN, INSULIN, POLYSACCHARIDES, MUCOPOLYSACCHARIDES EMISPHERE TECHNOLOGIES, INC. (US) 1999-11-23 US disclosed