Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448377 | 0.80 | ALDH1A1 (0.57) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL28500366 | 0.77 | ALDH1A1 (0.55) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL6448391 | 0.76 | MEN1 (0.40) | HPGDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6451368 | 0.75 | MAPT (0.45) | HPGDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL28501254 | 0.74 | ALDH1A1 (0.52) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL6452385 | 0.74 | ALDH1A1 (0.52) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL28488632 | 0.73 | ALDH1A1 (0.54) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL28504949 | 0.73 | ALDH1A1 (0.54) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL28492972 | 0.73 | ALDH1A1 (0.51) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL28502373 | 0.73 | ALDH1A1 (0.51) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | HPGD 258/4885RAB9A 2483/4885SMN1; SMN2 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.