SCHEMBL6449946

SCHEMBL6449946

OC1(OOC2(O)CCCCC2C2CCCCC2)CCCCC1C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.38
MAPT P10636 1/20 0.36
CYP2C19 P33261 1/20 0.32
HSD11B1 P28845 1/20 0.31
TSHR P16473 1/20 0.30
MET P08581 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815742 0.75 HSD17B10 (0.41) HSD17B10MAPTCYP2C19HSD11B1
SCHEMBL2575625 0.75 HSD17B10 (0.41) HSD17B10MAPTCYP2C19HSD11B1
SCHEMBL2573906 0.75 HSD17B10 (0.41) HSD17B10MAPTCYP2C19HSD11B1
SCHEMBL18784356 0.72 HSD17B10 (0.31) HSD17B10
SCHEMBL11151810 0.71 ALDH1A1 (0.47) HSD17B10MAPTHSD11B1
SCHEMBL27651835 0.71 HSD11B1 (0.36) HSD17B10HSD11B1
SCHEMBL11560173 0.70 HSD17B10 (0.33) HSD17B10
SCHEMBL4562939 0.70 HSD17B10 (0.59) HSD17B10MAPTHSD11B1TSHR
SCHEMBL10816509 0.70 HSD17B10 (0.59) HSD17B10MAPTHSD11B1TSHR
SCHEMBL1421632 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941261-B1 COMPOSITION NAT STARCH CHEM LTD (GB) 2005-05-25 EP disclosed
EP-0941261-A1 COMPOSITION National Starch and Chemical Limited (GB) 1999-09-15 EP disclosed
WO-1998023658-A1 COMPOSITION NATIONAL STARCH AND CHEMICAL LIMITED (GB) 1998-06-04 WO disclosed
EP-0627475-B1 Aerated anaerobic compositions with enhanced bulk stability LOCTITE IRELAND LTD (IE) 1998-03-25 EP disclosed
US-5567741-A STORAGE STABLE FOAM LOCTITE (IRELAND) LIMITED (IE) 1996-10-22 US disclosed
EP-0627475-A1 Aerated anaerobic compositions with enhanced bulk stability LOCTITE (IRELAND) LIMITED (IE) 1994-12-07 EP disclosed
US-4138449-A Anaerobic curing compositions BALDWIN TERENCE R 1979-02-06 US disclosed