Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771733 | 0.81 | MEN1 (0.44) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL4770756 | 0.69 | CYP3A4 (0.50) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL12330832 | 0.68 | KDM4E (0.54) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL14893886 | 0.67 | SCN9A (0.51) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL3375565 | 0.65 | CYP2D6 (0.44) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL7371817 | 0.64 | CA12 (0.50) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL19911128 | 0.64 | BRD4 (0.40) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL24554011 | 0.64 | MEN1 (0.55) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL20327145 | 0.64 | MEN1 (0.55) | MEN1KMT2AKDM4ELMNACASP1 | |
| SCHEMBL14828721 | 0.63 | POLB (0.70) | MEN1KMT2AHPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510545-A2 | 1,3 substituted 6-aminouraciles to stabilize halogenated polymers | Wehner, Wolfgang, Dr. (DE) | 2005-03-02 | — | — | EP | disclosed |
| EP-0967245-A1 | 1,3 substituted 6-aminouraciles to stabilize halogenated polymers | Witco Vinyl Additives GmbH (DE) | 1999-12-29 | — | — | EP | disclosed |