Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24554011 | 0.69 | MEN1 (0.55) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL20327145 | 0.69 | MEN1 (0.55) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL9395968 | 0.67 | BRD4 (0.44) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL4771733 | 0.66 | MEN1 (0.44) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL7371817 | 0.66 | CA12 (0.50) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL717117 | 0.65 | ALDH1A1 (0.50) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL27900581 | 0.65 | MEN1 (0.49) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL1795649 | 0.65 | ALDH1A1 (0.50) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL3817361 | 0.65 | ALDH1A1 (0.50) | CYP2D6KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL1730607 | 0.64 | MAPK1 (0.58) | KMT2AMEN1NPSR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386203-B1 | Use of dithiin tetracarboximides for combating phytopathogenic fungi | BAYER CROPSCIENCE AG (DE) | 2013-11-20 | — | — | EP | claimed |
| US-9095140-B2 | Use of dithiine-tetracarboximides for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| US-20150065551-A1 | Use of Dithiine-tetracarboximides for Controlling Phytopathogenic Fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-8865759-B2 | Use of dithiine-tetracarboximides for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-21 | — | — | US | disclosed |
| EP-2386203-B1 | Use of dithiin tetracarboximides for combating phytopathogenic fungi | BAYER CROPSCIENCE AG (DE) | 2013-11-20 | — | — | EP | disclosed |
| US-20110319462-A1 | Use of Dithiine-tetracarboximides for Controlling Phytopathogenic Fungi | BAYER CROPSCIENCE AG | 2011-12-29 | — | — | US | disclosed |
| US-20100120884-A1 | USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120884-A1 | USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI | TST, TTI1, DPM1 | CYP2D6 4458/4885KMT2A 2281/4885MEN1 1549/4885 |
| US-20110319462-A1 | Use of Dithiine-tetracarboximides for Controlling Phytopathogenic Fungi | TST, TTI1, DPM1 | CYP2D6 4458/4885KMT2A 2281/4885MEN1 1549/4885 |
| US-20150065551-A1 | Use of Dithiine-tetracarboximides for Controlling Phytopathogenic Fungi | TST, TTI1, DPM1 | CYP2D6 4458/4885KMT2A 2281/4885MEN1 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.