Serine

Serine

SCHEMBL6450168

NCC(=O)c1ccccc1.N[C@@H](CO)C(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC7A5 Q01650 1/20 0.47
KMO O15229 2/20 0.47
MAPK1 P28482 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
CES1 P23141 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SLC1A5 Q15758 1/20 0.44
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzoylmethane SCHEMBL1079375 0.87 KMT2A (0.63) TSHRALPIPKMPTGS1XIAP
Serine SCHEMBL8366514 0.83 NR4A2 (0.67) TSHRALPIPKMPTGS1XIAP
Serine SCHEMBL8366515 0.83 NR4A2 (0.67) TSHRALPIPKMPTGS1XIAP
SCHEMBL45515 0.82 MAPT (0.64) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL10337516 0.82 MAPT (0.64) TSHRMAPK1MEN1KMT2AMAPT
Benzamide SCHEMBL6443169 0.81 TSHR (0.61) TSHRALPIPKMPTGS1XIAP
SCHEMBL2860324 0.81 TSHR (0.64) TSHRALPIPKMPTGS1XIAP
SCHEMBL7799557 0.81 TSHR (0.64) TSHRALPIPKMPTGS1XIAP
SCHEMBL2791083 0.81 TSHR (0.64) TSHRALPIPKMPTGS1XIAP
Water SCHEMBL18694848 0.80 MAPT (0.61) TSHRMAPK1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050258406-A1 Black resist composition for color filter SHOWA DENKO K.K. 2005-11-24 US disclosed