Dibenzoylmethane

Dibenzoylmethane

SCHEMBL1079375

N[C@@H](CO)C(=O)O.O=C(CC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
CYP3A4 P08684 2/20 0.63
HPGD P15428 2/20 0.63
MAPK1 P28482 2/20 0.63
KDM4E B2RXH2 1/20 0.63
MAPT P10636 1/20 0.63
ALOX15 P16050 1/20 0.63
CES1 P23141 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
TSHR P16473 1/20 0.53
PLOD2 O00469 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HIF1A Q16665 2/20 0.52
NPC1 O15118 2/20 0.52
PLOD3 O60568 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL6450168 0.87 TSHR (0.52) KMT2AMEN1CYP3A4HPGDMAPK1
Serine SCHEMBL9498661 0.86 RAB9A (0.57) KMT2AMEN1CYP3A4HPGDMAPK1
Serine SCHEMBL8366514 0.84 NR4A2 (0.67) KMT2AMAPK1MAPTSMN1; SMN2TDP1
Serine SCHEMBL8366515 0.84 NR4A2 (0.67) KMT2AMAPK1MAPTSMN1; SMN2TDP1
Benzamide SCHEMBL6443169 0.83 TSHR (0.61) CYP3A4MAPTTDP1TSHRCYP2C19
SCHEMBL7799557 0.82 TSHR (0.64) KMT2AMEN1CYP3A4HPGDMAPK1
SCHEMBL2791083 0.82 TSHR (0.64) KMT2AMEN1CYP3A4HPGDMAPK1
SCHEMBL2860324 0.82 TSHR (0.64) KMT2AMEN1CYP3A4HPGDMAPK1
Thiobenzoic Acid SCHEMBL22611847 0.81 SLC7A5 (0.48) TSHRCYP1A2ALPIPKMPTGS1
Hydrochloric Acid SCHEMBL27416033 0.81 TSHR (0.62) KMT2AMEN1CYP3A4HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2447327-B1 Dispersion and process for producing colored organic solid particle DAICEL CHEM (JP) 2013-07-31 EP disclosed
EP-2450409-B1 Dispersion and process for producing colored organic solid particle DAICEL CHEM (JP) 2013-06-05 EP disclosed
EP-1690898-B1 DISPERSION AND PROCESS FOR PRODUCING COLORED ORGANIC SOLID PARTICLE DAICEL CHEM (JP) 2013-01-09 EP disclosed
EP-2450409-A1 Dispersion and process for producing colored organic solid particle Daicel Chemical Industries, Ltd. (JP) 2012-05-09 EP disclosed
EP-2447327-A1 Dispersion and process for producing colored organic solid particle Daicel Chemical Industries, Ltd. (JP) 2012-05-02 EP disclosed
US-8013042-B2 Process of producing a particle having a core-shell structure DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-09-06 US disclosed
US-20110163284-A1 LIGHTING UNIT COVER FUJIFILM CORPORATION (JP) 2011-07-07 US disclosed
EP-2330158-A1 LIGHTING COVER FUJIFILM Corporation (JP) 2011-06-08 EP disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
EP-2270113-A1 ULTRAVIOLET ABSORBENT COMPOSITIONS FUJIFILM Corporation (JP) 2011-01-05 EP disclosed
US-20090149572-A1 MULTIPLE PARTICLE AND COMPOSITION HAVING DISPERSE SYSTEM ITO HISAYOSHI 2009-06-11 US disclosed
US-7442730-B2 Composition having disperse system, and process for producing colored organic solid particle DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2008-10-28 US disclosed
EP-1908828-A1 NOVEL POLYPEPTIDE AND METHOD FOR PRODUCING THE SAME PHG Corporation (JP) 2008-04-09 EP disclosed
US-20070207180-A1 Synthetic polypeptide-containing bioapplicable material and film-forming material PHG CORPORATION (JP) 2007-09-06 US disclosed
US-20070125266-A1 Composition having disperse system, and process for producing colored organic solid particle DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-06-07 US disclosed
US-20070104951-A1 Multiple particle and composition having disperse system DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-05-10 US disclosed
EP-1693401-A1 COMPOSITE PARTICLE AND DISPERSION Daicel Chemical Industries, Ltd. (JP) 2006-08-23 EP disclosed
EP-1690898-A1 DISPERSION AND PROCESS FOR PRODUCING COLORED ORGANIC SOLID PARTICLE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-16 EP disclosed