Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262699 | 0.69 | — | — | |
| SCHEMBL712940 | 0.69 | — | — | |
| SCHEMBL7257636 | 0.65 | — | — | |
| SCHEMBL4178687 | 0.65 | — | — | |
| SCHEMBL1114546 | 0.65 | — | — | |
| SCHEMBL10771737 | 0.65 | HTT (0.42) | HTT | |
| SCHEMBL9305418 | 0.65 | HTT (0.42) | HTT | |
| SCHEMBL623307 | 0.65 | — | — | |
| SCHEMBL9212100 | 0.64 | — | — | |
| Phosphonic Acid SCHEMBL30542969 | 0.64 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234257-A1 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | LOYOLA UNIVERSITY OF CHICAGO | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234257-A1 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | PHOSPHO1, PAPSS1, PHPT1 | HTT 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.