SCHEMBL6450320

SCHEMBL6450320

C=C(C(=O)O)C(C)(C)CCC

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.35
FDPS P14324 2/20 0.34
ELANE P08246 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GGPS1 O95749 1/20 0.31
FFAR3 O14843 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6447500 0.86 GGPS1 (0.38) FDPSMEN1KMT2ATDP1ALDH1A1
SCHEMBL3775749 0.85 GGPS1 (0.45) FDPSGGPS1
SCHEMBL14245484 0.83 GGPS1 (0.48) FDPSGGPS1
SCHEMBL868945 0.81 TET2 (0.35) TET2
SCHEMBL10701254 0.81 LMNA (0.42) FDPSELANEMEN1KMT2ATDP1
SCHEMBL2138939 0.80 TET2 (0.38) TET2ALDH1A1FFAR3
SCHEMBL1963590 0.80 TET2 (0.38) TET2ALDH1A1FFAR3
Bromide SCHEMBL7118671 0.80 GGPS1 (0.46) FDPSGGPS1
SCHEMBL4986795 0.79 TET2 (0.34) TET2
SCHEMBL132663 0.79 TET2 (0.34) TET2FDPSTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102132358-A Conductive coating composition NISSAN CHEMICAL IND LTD 2011-07-20 CN disclosed
US-6916543-B2 Copolymer, photoresist compositions thereof and deep UV bilayer system thereof ARCH SPECIALTY CHEMICALS, INC. (US) 2005-07-12 US disclosed
US-20040137362-A1 Novel copolymer, photoresist compositions thereof and deep UV bilayer system thereof ARCH SPECIALTY CHEMICALS, INC. 2004-07-15 US disclosed
US-6462157-B1 DO NOT CONTAIN ANTIFLAME COMPOUNDS OF HALOGENATED TYPE AND/OR PHOSPHOR-BASED COMPOUNDS, YET ARE HEAT RESISTANT ATOFINA (FR) 2002-10-08 US disclosed
EP-0864695-A1 Antinoise sheets ATOHAAS HOLDING C.V. (NL) 1998-09-16 EP disclosed
EP-0557694-B1 Coating agents BASF AG (DE) 1997-04-23 EP disclosed
EP-0507141-B1 Compatible blends of aromatic poly-(ester)-carbonates and polyamides BAYER AG (DE) 1997-04-23 EP disclosed
EP-0485793-B1 Reinforced ABS-moulding matters containing graft polymers incorporating tert. alkyl esters, their manufacture and application BAYER AG (DE) 1995-02-08 EP disclosed
EP-0360129-B1 Molding compounds made of polyamides and tert.-butylacrylate containing graft polymers BAYER AG (DE) 1994-11-09 EP disclosed
EP-0355512-B1 Thermoplastic homogenisation products and their use in compositions of polyamide and copolymers and/or graft polymers of styrene BAYER AG (DE) 1994-09-21 EP disclosed
EP-0507141-A2 Compatible blends of aromatic poly-(ester)-carbonates and polyamides BAYER AG (DE) 1992-10-07 EP disclosed
EP-0485793-A1 Reinforced ABS-moulding matters containing graft polymers incorporating tert. alkyl esters, their manufacture and application BAYER AG (DE) 1992-05-20 EP disclosed
EP-0437693-A2 Mouldings based on polyamides and tert. alkylesters containing graft polymers BAYER AG (DE) 1991-07-24 EP disclosed
US-5010138-A Molding compounds of polyamides and styrene copolymers BAYER AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
US-4985486-A MOLDING MATERIALS, RUBBER MODIFIER FOR TOUGHNESS BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed
EP-0373439-A2 Process for controlling particle size in the preparation of polymers in powder form BASF Aktiengesellschaft (DE) 1990-06-20 EP disclosed
EP-0360129-A2 Molding compounds made of polyamides and tert.-butylacrylate containing graft polymers BAYER AG (DE) 1990-03-28 EP disclosed
EP-0355512-A2 Thermoplastic homogenisation products and their use in compositions of polyamide and copolymers and/or graft polymers of styrene BAYER AG (DE) 1990-02-28 EP disclosed
EP-0355510-A2 Reinforced/filled blends of thermoplastic interpolymers and polyamides and process for their preparation BAYER AG (DE) 1990-02-28 EP disclosed
EP-0283871-A2 Thermoplastic mouldings from polyamides and resinous copolymers BAYER AG (DE) 1988-09-28 EP disclosed