SCHEMBL868945

SCHEMBL868945

C=C(C(=O)O)C(C)(C)CCO

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.35
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL871547 0.86 CYP4F2 (0.44) TET2CYP4F2CYP4A11
SCHEMBL6450320 0.81 TET2 (0.35) TET2
SCHEMBL5080220 0.79 TET2 (0.43) TET2
SCHEMBL5080224 0.79 TET2 (0.43) TET2
SCHEMBL132663 0.79 TET2 (0.34) TET2
SCHEMBL4986795 0.79 TET2 (0.34) TET2
SCHEMBL23355960 0.77 TET2 (0.38) TET2
SCHEMBL6447500 0.77 GGPS1 (0.38)
Chloromethane SCHEMBL534660 0.77 TET2 (0.33) TET2
SCHEMBL492500 0.76 ODC1 (0.38) TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569639-B1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2025-09-24 EP disclosed
EP-2794723-B2 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2025-06-04 EP disclosed
EP-3181614-B9 SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY JOHNSON & JOHNSON VISION CARE (US) 2022-10-05 EP disclosed
EP-4011940-A1 SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY Johnson & Johnson Vision Care, Inc. (US) 2022-06-15 EP disclosed
EP-3181614-B1 SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY JOHNSON & JOHNSON VISION CARE (US) 2022-03-30 EP disclosed
EP-2794727-B2 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE (US) 2020-10-28 EP disclosed
EP-2794723-B9 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2019-11-20 EP disclosed
EP-3569639-A1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS Johnson & Johnson Vision Care Inc. (US) 2019-11-20 EP disclosed
US-10353115-B2 Silicone hydrogels comprising N-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides JOHNSON & JOHNSON VISION CARE, INC. (US) 2019-07-16 US disclosed
EP-2794723-B1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2019-04-24 EP disclosed
US-20140031447-A1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-01-30 US disclosed
US-20140024791-A1 SILICONE HYDROGELS COMPRISING N-VINYL AMIDES AND HYDROXYALKYL (METH)ACRYLATES OR (METH)ACRYLAMIDES JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-01-23 US disclosed
US-20130217620-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-08-22 US disclosed
US-20130172440-A1 SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-07-04 US disclosed
US-20130168617-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-07-04 US disclosed
WO-2013096587-A1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-06-27 WO disclosed
WO-2013096600-A1 SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-06-27 WO disclosed
WO-2013096604-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-06-27 WO disclosed
WO-2013096597-A1 SILICONE HYDROGELS COMPRISING N-VINYL AMIDES AND HYDROXYALKYL (METH)ACRYLATES OR (METH)ACRYLAMIDES JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-06-27 WO disclosed
US-20120076956-A1 Polarizing plate, liquid crystal display device using the same and moisture- and heat-resistant protective film for polarizing plate FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130217620-A1 IONIC SILICONE HYDROGELS HACD2, IGFBP2, IGFBP6 TET2 4423/4885CYP4F2 3630/4885CYP4A11 3495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.