SCHEMBL6450353

SCHEMBL6450353

OCC(c1ccccc1)c1cccc(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.53
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CACNA1G O43497 1/20 0.46
CACNA2D1 P54289 1/20 0.46
CACNA1B Q00975 1/20 0.46
CACNB1 Q02641 1/20 0.46
CACNA1C Q13936 1/20 0.46
LMNA P02545 2/20 0.45
ALDH1A1 P00352 2/20 0.45
CASR P41180 1/20 0.45
ALPL P05186 1/20 0.45
ALPI P09923 1/20 0.45
MAPT P10636 1/20 0.45
ALPG P10696 1/20 0.45
ALOX12 P18054 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10775144 0.96 ACP3 (0.52) ACP3MEN1KMT2ACACNA1GCACNA2D1
SCHEMBL14830681 0.92 ACP3 (0.46) ACP3MEN1KMT2ACACNA1GCACNA2D1
SCHEMBL11552637 0.87 HTR2A (0.44) ACP3LMNA
SCHEMBL4058257 0.83 IDO1 (0.50) MEN1KMT2ACACNA1GCACNA2D1CACNA1B
SCHEMBL193835 0.82 HTR2A (0.52) LMNA
SCHEMBL8324166 0.82 ACP3 (0.47) ACP3MEN1KMT2ACACNA1GCACNA2D1
SCHEMBL17071892 0.82 ACP3 (0.47) ACP3MEN1KMT2ACACNA1GCACNA2D1
SCHEMBL3415393 0.82 HTR2A (0.64) ACP3MEN1KMT2AIDO1TDO2
SCHEMBL8869652 0.81 MEN1 (0.56) ACP3MEN1KMT2ACACNA1GCACNA2D1
SCHEMBL8674097 0.81 MEN1 (0.49) ACP3MEN1KMT2ACACNA1GCACNA2D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3528776-B1 REDUCED-ETHANOL MOUTH RINSE FORMULATIONS KENVUE BRANDS LLC (US) 2025-11-26 EP disclosed
US-11857653-B2 Method of providing an oral care benefit using a poorly-soluble calcium compound and fluoride JOHNSON & JOHNSON CONSUMER INC. (US) 2024-01-02 US disclosed
US-11648186-B2 Coated particles and their uses JOHNSON & JOHNSON CONSUMER INC. (US) 2023-05-16 US disclosed
US-20220226205-A1 Coated Particles and Their Uses KENVUE BRANDS LLC 2022-07-21 US disclosed
US-11351103-B2 Method of providing oral care benefits JOHNSON & JOHNSON CONSUMER INC. (US) 2022-06-07 US disclosed
US-11291613-B2 Coated particles and their uses JOHNSON & JOHNSON CONSUMER INC. (US) 2022-04-05 US disclosed
EP-3897511-A1 METHOD OF PROVIDING AN ORAL CARE BENEFIT USING A POORLY-SOLUBLE CALCIUM COMPOUND AND FLUORIDE Johnson & Johnson Consumer Inc. (US) 2021-10-27 EP disclosed
EP-3270873-B1 CALCIUM-BASED DENTIFRICES FOR ENHANCED UPTAKE OF ACTIVE INGREDIENTS COLGATE PALMOLIVE CO (US) 2020-11-25 EP disclosed
WO-2020128680-A1 METHOD OF PROVIDING AN ORAL CARE BENEFIT USING A POORLY-SOLUBLE CALCIUM COMPOUND AND FLUORIDE JOHNSON & JOHNSON CONSUMER INC. (US) 2020-06-25 WO disclosed
US-20200188245-A1 Method of Providing an Oral Care Benefit using a Poorly-soluble Calcium Compound and Fluoride KENVUE BRANDS LLC 2020-06-18 US disclosed
US-5776435-A DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-07-07 US disclosed
EP-0565401-B1 Continuous process for making a non-newtonian paste or cream like material COLGATE PALMOLIVE CO (US) 1997-06-18 EP disclosed
US-5320832-A Low viscosity slurry; cosmetics or dentifrice COLGATE PALMOLIVE (US) 1994-06-14 US disclosed
US-5288480-A Antiplaque antibacterial oral composition COLGATE-PALMOLIVE CO. (US) 1994-02-22 US disclosed
EP-0565401-A1 Continuous process for making a non-newtonian paste or cream like material Colgate-Palmolive Company (US) 1993-10-13 EP disclosed
US-5236696-A High shear mixing of aqueous and non aqueous, low viscosity, homogeneous slurries; transforming to high viscosity in maturing tank with no agitation COLGATE-PALMOLIVE COMPANY (US) 1993-08-17 US disclosed
US-5178851-A Dentifrices treatment with triclosan and carriers COLGATE-PALMOLIVE COMPANY (US) 1993-01-12 US disclosed
US-5037635-A Antibacterial antiplaque oral composition COLATE-PALMOLIVE COMPANY (US) 1991-08-06 US disclosed
US-5032386-A Dentistry COLGATE-PALMOLIVE COMPANY (US) 1991-07-16 US disclosed
US-4894220-A WATER AND ALCOHOL SOLVENTS, GLYCOL DERIVATIVES AND ESTERS SOLUTIONS COLGATE-PALMOLIVE COMPANY (US) 1990-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291613-B2 Coated particles and their uses CD63, EPCAM, CD44 ACP3 398/4885MEN1 3074/4885KMT2A 2405/4885
US-11648186-B2 Coated particles and their uses CD63, EPCAM, CD44 ACP3 398/4885MEN1 3074/4885KMT2A 2405/4885
US-20220226205-A1 Coated Particles and Their Uses CD63, EPCAM, CD44 ACP3 398/4885MEN1 3074/4885KMT2A 2405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.