Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450353 | 0.82 | ACP3 (0.53) | ACP3MEN1KMT2ACACNA1GCACNA2D1 | |
| SCHEMBL7429108 | 0.81 | IDO1 (0.50) | CACNA1GCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL3415393 | 0.80 | HTR2A (0.64) | ACP3MEN1KMT2AIDO1TDO2 | |
| SCHEMBL94275 | 0.80 | HTR2A (0.52) | LMNA | |
| SCHEMBL17071892 | 0.80 | ACP3 (0.47) | ACP3MEN1KMT2ACACNA1GCACNA2D1 | |
| Hydrochloric Acid SCHEMBL10707847 | 0.78 | HTR2A (0.61) | ACP3MEN1KMT2ALMNAIDO1 | |
| SCHEMBL8326192 | 0.78 | SLC6A2 (0.50) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL10775144 | 0.77 | ACP3 (0.52) | ACP3MEN1KMT2ACACNA1GCACNA2D1 | |
| SCHEMBL27721198 | 0.77 | AHR (0.50) | ALDH1A1SLC6A2SLC6A4HPGD | |
| SCHEMBL4375119 | 0.76 | ACP3 (0.50) | ACP3MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948496-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDONE COMPOUNDS AND METHODS OF USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024780-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |