Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390910 | 0.87 | CYP2D6 (0.60) | CYP3A4CYP2D6KDM4EMEN1ALDH1A1 | |
| SCHEMBL12806555 | 0.79 | ESR1 (0.48) | MEN1KMT2ACYP2C19CYP1A2POLQ | |
| SCHEMBL1265069 | 0.79 | SLC6A4 (0.61) | CYP3A4CYP2D6KDM4EALDH1A1MAPT | |
| SCHEMBL20509493 | 0.77 | CYP3A4 (0.57) | CYP3A4CYP2D6KDM4EMEN1ALDH1A1 | |
| SCHEMBL29793859 | 0.77 | CYP3A4 (0.57) | CYP3A4CYP2D6KDM4EMEN1ALDH1A1 | |
| SCHEMBL6128132 | 0.77 | KDM4E (0.61) | KDM4EMEN1ALDH1A1POLBGAA | |
| SCHEMBL1045742 | 0.77 | KLF10 (0.46) | KDM4EMEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL3930119 | 0.77 | CYP3A4 (0.54) | CYP3A4CYP2D6KDM4EALDH1A1SLC6A4 | |
| SCHEMBL28205058 | 0.77 | CYP3A4 (0.50) | CYP3A4CYP2D6KDM4EALDH1A1SLC6A4 | |
| SCHEMBL4236353 | 0.76 | SLC6A4 (0.61) | CYP3A4CYP2D6SLC6A4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903239-B2 | Fluorinated benzaldehydes | BAYER CHEMICAL AKTIENGESELLSCHAFT (DE) | 2005-06-07 | — | — | US | claimed |
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | claimed |
| US-20040133043-A1 | Fluorinated benzaldehydes | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-08 | — | — | US | claimed |
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1428814-A1 | Fluorine containing benzaldehydes | Bayer Chemicals AG (DE) | 2004-06-16 | — | — | EP | claimed |
| US-6903239-B2 | Fluorinated benzaldehydes | BAYER CHEMICAL AKTIENGESELLSCHAFT (DE) | 2005-06-07 | — | — | US | disclosed |
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
| US-20040133043-A1 | Fluorinated benzaldehydes | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-08 | — | — | US | disclosed |
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| EP-1428814-A1 | Fluorine containing benzaldehydes | Bayer Chemicals AG (DE) | 2004-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133043-A1 | Fluorinated benzaldehydes | PFAS, FIP1L1, AFF2 | CYP3A4 216/4885CYP2D6 406/4885KDM4E 1421/4885 |
| US-20040171864-A1 | Fluorinated aromatics | AFF1, AFF2, AFF4 | CYP3A4 55/4885CYP2D6 233/4885KDM4E 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.