Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13607511 | 0.82 | LMNA (0.43) | LMNAEPHX1SIGMAR1POLBALDH1A1 | |
| SCHEMBL6450396 | 0.80 | EPHX1 (0.50) | LMNAEPHX1SMN1; SMN2POLBUSP2 | |
| SCHEMBL13294283 | 0.78 | EPHX1 (0.60) | LMNAEPHX1SMN1; SMN2POLBUSP2 | |
| SCHEMBL3684347 | 0.78 | EPHX1 (0.60) | LMNAEPHX1SMN1; SMN2POLBUSP2 | |
| SCHEMBL176407 | 0.77 | — | — | |
| Fluoride SCHEMBL27304026 | 0.77 | EPHX1 (0.65) | LMNAEPHX1SMN1; SMN2POLBUSP2 | |
| SCHEMBL21869508 | 0.77 | EPHX1 (0.46) | LMNAEPHX1SIGMAR1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL11412369 | 0.76 | EPHX1 (0.46) | LMNAEPHX1SMN1; SMN2POLBUSP2 | |
| SCHEMBL587972 | 0.76 | — | — | |
| SCHEMBL3025639 | 0.76 | LMNA (0.39) | LMNASIGMAR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525235-A1 | MICROSTRUCTURE CHAIN TRANSFER AGENTS FOR ANIONIC POLYMERIZATION | Hellermann, Walter (DE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004014966-A1 | MICROSTRUCTURE CHAIN TRANSFER AGENTS FOR ANIONIC POLYMERIZATION | HELLERMANN WALTER (DE) | 2004-02-19 | — | — | WO | claimed |