Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684347 | 0.80 | EPHX1 (0.60) | EPHX1LMNAALDH1A1TP53HPGD | |
| SCHEMBL13294283 | 0.80 | EPHX1 (0.60) | EPHX1LMNAALDH1A1TP53HPGD | |
| SCHEMBL15308496 | 0.79 | ALDH1A1 (0.41) | EPHX1LMNAALDH1A1HPGDKMT2A | |
| SCHEMBL15308549 | 0.79 | ALDH1A1 (0.41) | EPHX1LMNAALDH1A1HPGDKMT2A | |
| SCHEMBL11306190 | 0.77 | ALDH1A1 (0.40) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL6450378 | 0.77 | LMNA (0.53) | EPHX1LMNAALDH1A1SIGMAR1TP53 | |
| SCHEMBL4626384 | 0.74 | EPHX1 (0.80) | EPHX1LMNAALDH1A1TP53HPGD | |
| SCHEMBL538474 | 0.74 | EPHX1 (0.80) | EPHX1LMNAALDH1A1TP53HPGD | |
| SCHEMBL18825665 | 0.74 | EPHX1 (0.80) | EPHX1LMNAALDH1A1TP53HPGD | |
| SCHEMBL5515259 | 0.74 | EPHX1 (0.80) | EPHX1LMNAALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914234-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |