Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448299 | 0.87 | CYP1A2 (0.38) | HTR2AABCB1TAAR1 | |
| SCHEMBL6450496 | 0.84 | TAAR1 (0.45) | HTR2AMAOBBCHEHTR1ATAAR1 | |
| SCHEMBL6451089 | 0.82 | KDM4E (0.41) | HTR2AMAOBDRD2TAAR1 | |
| SCHEMBL6451103 | 0.80 | PARP15 (0.43) | ABCB1TAAR1 | |
| SCHEMBL7072303 | 0.72 | NR3C1 (0.40) | MAOBBCHEPTPN7DUSP3TAAR1 | |
| SCHEMBL8009626 | 0.72 | CYP1A2 (0.44) | TAAR1 | |
| SCHEMBL429765 | 0.72 | TAAR1 (0.63) | DRD2TAAR1 | |
| SCHEMBL24221004 | 0.71 | KMT2A (0.59) | HTR2AABCB1TAAR1 | |
| SCHEMBL9145125 | 0.71 | CYP1A2 (0.46) | TAAR1 | |
| SCHEMBL28128268 | 0.71 | ABCB1 (0.54) | ABCB1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | claimed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | claimed |