Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451103 | 0.85 | PARP15 (0.43) | KDM4ETAAR1ADRA1ACYP1A2NPC1 | |
| SCHEMBL6451086 | 0.83 | ALDH1A1 (0.48) | KDM4EALDH1A1HTR2AHTR2CDAO | |
| SCHEMBL6450498 | 0.82 | HTR2A (0.47) | TAAR1DRD2HTR2AMAOB | |
| SCHEMBL6448299 | 0.81 | CYP1A2 (0.38) | ALDH1A1TAAR1CYP1A2HTR2AHMGCR | |
| SCHEMBL6459893 | 0.76 | CYP1A2 (0.45) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL30636758 | 0.74 | IDO1 (0.50) | KDM4EALDH1A1HTR2AHTR2CKCNH2 | |
| SCHEMBL1709322 | 0.74 | IDO1 (0.50) | KDM4EALDH1A1HTR2AHTR2CKCNH2 | |
| SCHEMBL8009626 | 0.74 | CYP1A2 (0.44) | ALDH1A1TAAR1CYP1A2SMN1; SMN2HMGCR | |
| SCHEMBL9145125 | 0.73 | CYP1A2 (0.46) | ALDH1A1TAAR1ADRA1ACYP1A2APLNR | |
| SCHEMBL9921244 | 0.72 | TAAR1 (0.46) | TAAR1ADRA1ACYP1A2APLNRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | claimed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | claimed |