Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451576 | 0.95 | MEN1 (0.39) | SCN9APTGS1PTGS2MGLLFAAH | |
| SCHEMBL2486662 | 0.89 | PGR (0.37) | CYP19A1 | |
| SCHEMBL13341347 | 0.85 | ALDH1A1 (0.35) | — | |
| SCHEMBL2486986 | 0.85 | TDP1 (0.54) | SCN9APTGS1PTGS2MGLLFAAH | |
| SCHEMBL2491069 | 0.84 | SCN9A (0.37) | SCN9APTGS1PTGS2MGLLFAAH | |
| SCHEMBL13341348 | 0.83 | MPI (0.32) | — | |
| SCHEMBL2486094 | 0.83 | AURKA (0.44) | MGLLCYP19A1 | |
| SCHEMBL2489388 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL13341332 | 0.82 | SCN9A (0.39) | SCN9A | |
| Hydrochloric Acid SCHEMBL10696532 | 0.81 | AURKA (0.43) | MGLLCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714010-B2 | Pyrrolobenzimidazolones and their use as anti-proliferative agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-11 | — | — | US | disclosed |
| US-7714010-B2 | Pyrrolobenzimidazolones and their use as anti-proliferative agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-11 | — | — | US | disclosed |
| EP-1598353-A1 | Pyrrolobenzimidazolones and their use as antiproliferative agents | Boehringer Ingelheim International GmbH (DE) | 2005-11-23 | — | — | EP | disclosed |