⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426806 | 0.78 | ALDH1A1 (0.55) | — | |
| SCHEMBL2528624 | 0.71 | — | — | |
| SCHEMBL20885 | 0.71 | — | — | |
| SCHEMBL2984543 | 0.71 | — | — | |
| SCHEMBL197720 | 0.71 | — | — | |
| SCHEMBL1205072 | 0.71 | — | — | |
| SCHEMBL5629839 | 0.71 | — | — | |
| SCHEMBL2683514 | 0.71 | — | — | |
| SCHEMBL20722189 | 0.71 | — | — | |
| SCHEMBL1028042 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975259-B2 | Compositions and methods for inhibiting G protein signaling | UNIVERSITY OF ROCHESTER (US) | 2015-03-10 | — | — | US | claimed |
| US-20100130505-A1 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2010-05-27 | — | — | US | claimed |
| EP-2147310-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | University of Rochester (US) | 2010-01-27 | — | — | EP | claimed |
| WO-2009020677-A9 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIV ROCHESTER (US) | 2009-04-16 | — | — | WO | claimed |
| WO-2009020677-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2009-02-12 | — | — | WO | claimed |
| CN-1308296-C | Process for purifying 2,5 diamino phenyl-1,3-disulfonic acid | SHANGHAI CHEMICAL REAGENT INST (CN) | 2007-04-04 | — | — | CN | claimed |
| CN-1623981-A | Process for purifying 2,5 diamino phenyl-1,3-disulfonic acid | SHANGHAI CHEMICAL REAGENT INST (CN) | 2005-06-08 | — | — | CN | claimed |
| CN-109134861-A | A kind of preparation method of the fire-retardant polyimides new material of solubility | 王金桢 | 2019-01-04 | — | — | CN | disclosed |
| CN-108699241-A | Polyalkyleneimino polymers with polyester groups | 巴斯夫欧洲公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-107548301-A | Contain composition of the menthol as soothing agent | 西姆莱斯股份公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-103622842-B | Delivery of particles | 宝洁公司 | 2017-10-27 | — | — | CN | disclosed |
| US-9560848-B2 | Method and compositions for biofouling deterrence | CLEMSON UNIVERSITY (US) | 2017-02-07 | — | — | US | disclosed |
| CN-102858944-B | Delivery of particles | 宝洁公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| EP-0138766-A2 | Process for the preparation of substituted 1-phenyl indanes | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4338436-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338439-A | BACTERICIDAL ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4319028-A | 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4311478-A | HAIR DYES | L'OREAL (FR) | 1982-01-19 | — | — | US | disclosed |
| US-4152112-A | Dyeing composition for keratinic fibers containing paraphenylenediamines | L'OREAL (FR) | 1979-05-01 | — | — | US | disclosed |