Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451086 | 0.84 | ALDH1A1 (0.48) | ABCB1HTR2AHTR2CTUBB4ATUBB | |
| SCHEMBL6451103 | 0.83 | PARP15 (0.43) | ABCB1PARP15PARP10TAAR1ALOX5 | |
| SCHEMBL27612616 | 0.79 | ABCB1 (0.46) | ABCB1ABCG2HTR2AHTR2CHTR2B | |
| SCHEMBL6448298 | 0.78 | HMGCR (0.41) | HTR2AHTR2CHTR2BTUBB4ATUBB | |
| SCHEMBL6450496 | 0.78 | TAAR1 (0.45) | HTR2AHTR2CHTR2BBCHETAAR1 | |
| SCHEMBL6452983 | 0.77 | HTR2A (0.39) | HTR2AHTR2CHTR2BTAAR1TUBB4A | |
| SCHEMBL6449528 | 0.76 | ALDH1A1 (0.40) | HTR2AHTR2CHTR2BTUBB4ATUBB | |
| SCHEMBL30866618 | 0.73 | TAAR1 (0.62) | TAAR1 | |
| SCHEMBL172266 | 0.73 | TAAR1 (0.62) | TAAR1 | |
| Hydrochloric Acid SCHEMBL25186690 | 0.73 | HTR2A (0.61) | HTR2AHTR2CHTR2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | claimed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | claimed |