SCHEMBL6451307

SCHEMBL6451307

N#COC1(OC#N)CCc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.41
MAOB P27338 1/20 0.41
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTR2A P28223 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
HDAC9 Q9UKV0 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15547835 0.75 KDM1A (0.44) KDM1AMAOBTSHRTDP1MEN1
SCHEMBL16136583 0.71 KDM1A (0.39) KDM1AMAOBTSHRTDP1MEN1
SCHEMBL12247403 0.68 SIGMAR1 (0.43) KDM1AMAOBTSHRALDH1A1TP53
SCHEMBL28223963 0.68 KDM1A (0.46) KDM1AMAOBTSHRTDP1HTR2A
SCHEMBL412891 0.67 KDM1A (0.48) KDM1AMAOBTSHRTDP1MEN1
SCHEMBL29529565 0.67 KDM1A (0.48) KDM1AMAOBTSHRTDP1MEN1
SCHEMBL27908726 0.67 KDM1A (0.48) KDM1AMAOBTSHRTDP1MEN1
SCHEMBL666915 0.66 HTR2A (0.55) KDM1AMAOBTSHRTDP1HTR2A
Ammonia Solution, Strong SCHEMBL27832849 0.66 KDM1A (0.47) KDM1AMAOBTSHRTDP1MEN1
Hydrochloric Acid SCHEMBL27330764 0.66 KDM1A (0.47) KDM1AMAOBTSHRTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030069384-A1 Preparation of polyindanebisphenols and polymers derived therefrom HONEYWELL INTERNATIONAL INC. 2003-04-10 US claimed
EP-1056699-A1 PREPARATION OF POLYINDANEBISPHENOLS AND POLYMERS DERIVED THEREFROM Alliedsignal, Inc. (US) 2000-12-06 EP claimed
US-6153721-A CRACKING BISPHENOL A TO PRODUCE A MIXTURE COMPRISING P-ISOPROPENYLPHENOL AND PHENOL, COPOLYMERIZING THE RESULTING MIXTURE WITH AN ISOPROPENYLBENZENE COMPOUND IN A SUITABLE POLYMERIZATION MEDIUM TO YIELD A POLYINDANEBISPHENOL. HONEYWELL INTERNATIONAL INC. (US) 2000-11-28 US claimed
WO-1999043638-A1 PREPARATION OF POLYINDANEBISPHENOLS AND POLYMERS DERIVED THEREFROM ALLIEDSIGNAL INC. (US) 1999-09-02 WO claimed
US-6858304-B2 Preparation of polyindanebisphenols and polymers derived therefrom HONEYWELL INTERNATIONAL INC. (US) 2005-02-22 US disclosed
US-20030069384-A1 Preparation of polyindanebisphenols and polymers derived therefrom HONEYWELL INTERNATIONAL INC. 2003-04-10 US disclosed
US-6509063-B1 Copolymerization with such as epoxy resin, epoxy function-alized elastomer or amorphous polycarbonate; impregnating monomer solution on fibrous support and desolvating to form dry laminate HONEYWELL INTERNATIONAL INC. 2003-01-21 US disclosed
EP-1056699-A1 PREPARATION OF POLYINDANEBISPHENOLS AND POLYMERS DERIVED THEREFROM Alliedsignal, Inc. (US) 2000-12-06 EP disclosed
US-6153721-A CRACKING BISPHENOL A TO PRODUCE A MIXTURE COMPRISING P-ISOPROPENYLPHENOL AND PHENOL, COPOLYMERIZING THE RESULTING MIXTURE WITH AN ISOPROPENYLBENZENE COMPOUND IN A SUITABLE POLYMERIZATION MEDIUM TO YIELD A POLYINDANEBISPHENOL. HONEYWELL INTERNATIONAL INC. (US) 2000-11-28 US disclosed
WO-1999043638-A1 PREPARATION OF POLYINDANEBISPHENOLS AND POLYMERS DERIVED THEREFROM ALLIEDSIGNAL INC. (US) 1999-09-02 WO disclosed