SCHEMBL645134

SCHEMBL645134

Cc1sccc1C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL977074 0.75
SCHEMBL10388465 0.75
SCHEMBL23160735 0.74 ALDH1A1 (0.42)
SCHEMBL1419542 0.74 CYP2A6 (0.45)
SCHEMBL225281 0.72
SCHEMBL13505 0.71
SCHEMBL10239997 0.71
SCHEMBL7869745 0.70 HCAR2 (0.47)
SCHEMBL134580 0.70
SCHEMBL15888128 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638438-A1 ALPHA4 BETA7 INTEGRIN ANTAGONISTS AND USES THEREOF Xinthera, Inc. (US) 2025-10-29 EP disclosed
US-20250290009-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING FIRMENICH SA (CH) 2025-09-18 US disclosed
EP-4522714-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING Firmenich SA (CH) 2025-03-19 EP disclosed
CN-118908981-A Method for producing organometallic nucleophile and reaction method using organometallic nucleophile 国立大学法人北海道大学 2024-11-08 CN disclosed
US-20240279214-A1 ALPHA4 BETA7 INEGRIN ANTAGONISTS AND USES THEREOF XINTHERA, INC. 2024-08-22 US disclosed
WO-2024138042-A1 ALPHA4 BETA7 INTEGRIN ANTAGONISTS AND USES THEREOF XINTHERA, INC. (US) 2024-06-27 WO disclosed
WO-2024138042-A1 ALPHA4 BETA7 INTEGRIN ANTAGONISTS AND USES THEREOF XINTHERA, INC. (US) 2024-06-27 WO disclosed
CN-117903170-A Light-operated chiral ligand based on diarylethene and light-operated asymmetric catalysis application thereof 华东理工大学 2024-04-19 CN disclosed
EP-4310067-A1 METHOD FOR PRODUCING ORGANIC METAL NUCLEOPHILIC AGENT AND REACTION METHOD USING ORGANIC METAL NUCLEOPHILIC AGENT National University Corporation Hokkaido University (JP) 2024-01-24 EP disclosed
WO-2023217712-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING FIRMENICH SA (CH) 2023-11-16 WO disclosed
EP-0954521-A1 4- (THIEN-3-YL)METHYL] IMIDAZOLE DERIVATIVES HAVING ALPHA2-ADRENOCEPTOR AGONISTIC ACTIVITY Ortho-McNeil Pharmaceutical, Inc. (US) 1999-11-10 EP disclosed
US-5760259-A MYRISTIC ACID DERIVATIVES CAPABLE OF INHIBITING BIOSYNTHESIS OF PARASITE'S ANCHORING GROUP WASHINGTON UNIVERSITY (US) 1998-06-02 US disclosed
US-5750720-A ALPHA-ADRENORECEPTORS AND CENTRAL NERVOUS SYSTEMS ORTHO PHARMACEUTICAL CORPORATION (US) 1998-05-12 US disclosed
US-5747537-A Method of inhibiting parasitic activity WASHINGTON UNIVERSITY (US) 1998-05-05 US disclosed
EP-0811008-A1 BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS American Cyanamid Company (US) 1997-12-10 EP disclosed
WO-1997035858-A1 4-[(THIEN-3-YL)METHYL] IMIDAZOLE DERIVATIVES HAVING α2-ADRENOCEPTOR AGONISTIC ACTIVITY ORTHO PHARMACEUTICAL CORPORATION (US) 1997-10-02 WO disclosed
US-5510346-A ANTIDEPRESSANTS, ANTIANXIETY AGENTS HOECHST MARION ROUSSEL, INC. (US) 1996-04-23 US disclosed
EP-0315115-B1 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives, process for producing them and use thereof MOCHIDA PHARM CO LTD (JP) 1994-06-15 EP disclosed
US-5292760-A 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1994-03-08 US disclosed
EP-0322582-A2 4-Heteroaryl-1,3-Benzodiazepines and 2-substituted-alpha-(heteroaryl)benzeneethanamines, a process for their preparation and their use us medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-07-05 EP disclosed