⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849954 | 0.82 | F2 (0.35) | — | |
| SCHEMBL7801495 | 0.76 | PDE4B (0.34) | — | |
| SCHEMBL199019 | 0.76 | MAPK14 (0.32) | — | |
| SCHEMBL12087415 | 0.67 | — | — | |
| SCHEMBL18723458 | 0.66 | — | — | |
| SCHEMBL10154239 | 0.66 | MRGPRX2 (0.50) | — | |
| SCHEMBL13774864 | 0.61 | ITGA4 (0.35) | — | |
| SCHEMBL8549931 | 0.61 | — | — | |
| SCHEMBL247854 | 0.61 | — | — | |
| SCHEMBL8277333 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581533-A2 | NOVEL BENZONAPHTHYRIDINES | ALTANA Pharma AG (DE) | 2005-10-05 | — | — | EP | claimed |
| WO-2004018465-A9 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2005-09-15 | — | — | WO | claimed |
| WO-2004018465-A2 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | claimed |
| EP-1581533-A2 | NOVEL BENZONAPHTHYRIDINES | ALTANA Pharma AG (DE) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004018465-A9 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2005-09-15 | — | — | WO | disclosed |
| WO-2004018465-A2 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | disclosed |