Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451785 | 1.00 | GAA (0.41) | GAASMN1; SMN2ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL6457292 | 0.89 | TTR (0.38) | GRIN1GRIN2BMAPT | |
| SCHEMBL6457287 | 0.89 | TTR (0.38) | GRIN1GRIN2BMAPT | |
| SCHEMBL6452790 | 0.89 | TRPA1 (0.33) | GAASMN1; SMN2 | |
| SCHEMBL6452794 | 0.89 | TRPA1 (0.33) | GAASMN1; SMN2 | |
| SCHEMBL6458878 | 0.88 | IDH1 (0.33) | GAASMN1; SMN2FASN | |
| SCHEMBL6458873 | 0.88 | IDH1 (0.33) | GAASMN1; SMN2FASN | |
| SCHEMBL6457280 | 0.88 | SMN1; SMN2 (0.38) | GAASMN1; SMN2ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL6457275 | 0.88 | SMN1; SMN2 (0.38) | GAASMN1; SMN2ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL6455915 | 0.88 | TDP1 (0.41) | GAASMN1; SMN2ALDH1A1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |