Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458878 | 1.00 | IDH1 (0.33) | IDH1FASNGAASMN1; SMN2KDM1A | |
| SCHEMBL6455056 | 0.89 | MAPT (0.32) | — | |
| SCHEMBL6455059 | 0.89 | MAPT (0.32) | — | |
| SCHEMBL6452794 | 0.89 | TRPA1 (0.33) | GAASMN1; SMN2KDM1A | |
| SCHEMBL6452790 | 0.89 | TRPA1 (0.33) | GAASMN1; SMN2KDM1A | |
| SCHEMBL6451785 | 0.88 | GAA (0.41) | FASNGAASMN1; SMN2 | |
| SCHEMBL6451782 | 0.88 | GAA (0.41) | FASNGAASMN1; SMN2 | |
| SCHEMBL6456829 | 0.88 | FASN (0.33) | IDH1FASNGAASMN1; SMN2KDM1A | |
| SCHEMBL6456828 | 0.88 | FASN (0.33) | IDH1FASNGAASMN1; SMN2KDM1A | |
| SCHEMBL6454829 | 0.88 | FASN (0.34) | IDH1FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |