Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451883 | 1.00 | KDM1A (0.40) | KDM1ATRPV4CYP11B1CYP11B2CHEK1 | |
| SCHEMBL14228793 | 0.87 | KDM1A (0.41) | KDM1ATRPV4CYP11B1CYP11B2CHEK1 | |
| SCHEMBL6452218 | 0.86 | SLC6A4 (0.39) | KDM1A | |
| SCHEMBL6452212 | 0.86 | SLC6A4 (0.39) | KDM1A | |
| SCHEMBL14274413 | 0.86 | KDM1A (0.43) | KDM1ATRPV4CYP11B1CYP11B2CHEK1 | |
| SCHEMBL31343 | 0.86 | KDM1A (0.43) | KDM1ATRPV4CYP11B1CYP11B2CHEK1 | |
| SCHEMBL6459846 | 0.83 | TRPV4 (0.35) | KDM1ATRPV4CYP11B1CYP11B2CHEK1 | |
| SCHEMBL6459842 | 0.83 | TRPV4 (0.35) | KDM1ATRPV4CYP11B1CYP11B2CHEK1 | |
| SCHEMBL6454732 | 0.83 | SLC6A4 (0.32) | KDM1A | |
| SCHEMBL6454736 | 0.83 | SLC6A4 (0.32) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |