Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.60 |
| ▸ | F10 | P00742 | 3/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.60 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | KLK1 | P06870 | 4/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455654 | 0.83 | F2 (0.46) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6457229 | 0.76 | F2 (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6455724 | 0.75 | F2 (0.39) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6450643 | 0.75 | F2 (0.40) | F2F10PRSS1PLGKLK1 | |
| SCHEMBL4451561 | 0.75 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7450241 | 0.75 | F2 (0.57) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6450440 | 0.75 | KLK1 (0.38) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7410692 | 0.75 | F2 (0.98) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7460376 | 0.74 | F2 (0.97) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7450587 | 0.73 | F2 (0.52) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | claimed |
| EP-1517687-A1 | MEDICAMENT FOR THE TREATMENT OF THE SYSTEMIC INFLAMMATORY RESPONSE SYNDROME | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000310-A1 | MEDICAMENT FOR THE TREATMENT OF THE SYSTEMIC INFLAMMATORY RESPONSE SYNDROME | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-12-31 | — | — | WO | disclosed |
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |