Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.57 |
| ▸ | F10 | P00742 | 5/20 | 0.57 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 4/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442317 | 0.87 | F2 (0.54) | F2F10PLGKLK1KLK5 | |
| SCHEMBL4450206 | 0.80 | F2 (0.87) | F2F10PLGKLK1KLK5 | |
| Hydrochloric Acid SCHEMBL7411878 | 0.79 | F2 (0.86) | F2F10PLGKLK1KLK5 | |
| SCHEMBL6450440 | 0.79 | KLK1 (0.38) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7450500 | 0.79 | MLLT1 (0.39) | F2F10MLLT1 | |
| SCHEMBL7450226 | 0.79 | F2 (0.49) | F2F10KLK1KLK5PRSS1 | |
| SCHEMBL7424427 | 0.79 | F2 (0.42) | F2F10PLGKLK1KLK5 | |
| SCHEMBL7453719 | 0.79 | F2 (0.42) | F2F10PLGKLK1KLK5 | |
| Hydrochloric Acid SCHEMBL7445570 | 0.78 | F2 (0.48) | F2F10KLK1KLK5PRSS1 | |
| SCHEMBL7422210 | 0.78 | F2 (0.40) | F2F10PLGKLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | claimed |
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |