Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451948 | 1.00 | CTSK (0.38) | CTSKNAAACYP2C9ALDH1A1LMNA | |
| SCHEMBL6452975 | 0.94 | CTSK (0.37) | CTSKNAAACYP2C9EPHX2PDE2A | |
| SCHEMBL6452981 | 0.94 | CTSK (0.37) | CTSKNAAACYP2C9EPHX2PDE2A | |
| SCHEMBL12032032 | 0.94 | CTSK (0.40) | CTSKNAAACYP2C9ALDH1A1LMNA | |
| SCHEMBL6453660 | 0.93 | CTSK (0.36) | CTSKNAAAMAPTEPHX2PDE2A | |
| SCHEMBL6453654 | 0.93 | CTSK (0.36) | CTSKNAAAMAPTEPHX2PDE2A | |
| SCHEMBL6454875 | 0.92 | CTSK (0.36) | CTSKNAAAMAPTEPHX2PDE2A | |
| SCHEMBL6457817 | 0.92 | CTSK (0.36) | CTSKNAAAMAPTEPHX2PDE2A | |
| SCHEMBL6454871 | 0.92 | CTSK (0.36) | CTSKNAAAMAPTEPHX2PDE2A | |
| SCHEMBL6457815 | 0.92 | CTSK (0.36) | CTSKNAAAMAPTEPHX2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |