Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454875 | 1.00 | CTSK (0.36) | CTSKNAAAMGLLEPHX2GAA | |
| SCHEMBL6457817 | 1.00 | CTSK (0.36) | CTSKNAAAMGLLEPHX2GAA | |
| SCHEMBL6457815 | 1.00 | CTSK (0.36) | CTSKNAAAMGLLEPHX2GAA | |
| SCHEMBL6453654 | 0.99 | CTSK (0.36) | CTSKNAAAMGLLEPHX2GAA | |
| SCHEMBL6453660 | 0.99 | CTSK (0.36) | CTSKNAAAMGLLEPHX2GAA | |
| SCHEMBL6452981 | 0.96 | CTSK (0.37) | CTSKNAAAMGLLEPHX2PDE2A | |
| SCHEMBL6452975 | 0.96 | CTSK (0.37) | CTSKNAAAMGLLEPHX2PDE2A | |
| SCHEMBL6451948 | 0.92 | CTSK (0.38) | CTSKNAAAEPHX2MAPTPDE2A | |
| SCHEMBL6451944 | 0.92 | CTSK (0.38) | CTSKNAAAEPHX2MAPTPDE2A | |
| SCHEMBL6464177 | 0.92 | GAA (0.33) | MGLLGAAMAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |