Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451967 | 1.00 | PRSS1 (0.39) | PRSS1ACRSRD5A1SRD5A2TRPV1 | |
| SCHEMBL6453527 | 0.91 | EPHX2 (0.36) | MAPTLIPETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6453530 | 0.91 | EPHX2 (0.36) | MAPTLIPETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6457287 | 0.90 | TTR (0.38) | SRD5A1SRD5A2MEN1KMT2AMAPT | |
| SCHEMBL6457292 | 0.90 | TTR (0.38) | SRD5A1SRD5A2MEN1KMT2AMAPT | |
| SCHEMBL6455915 | 0.89 | TDP1 (0.41) | PRSS1ACRTRPV1SMN1; SMN2MEN1 | |
| SCHEMBL6452087 | 0.89 | ALDH1A1 (0.40) | PRSS1ACRSRD5A1SRD5A2SMN1; SMN2 | |
| SCHEMBL6452092 | 0.89 | ALDH1A1 (0.40) | PRSS1ACRSRD5A1SRD5A2SMN1; SMN2 | |
| SCHEMBL6455921 | 0.89 | TDP1 (0.41) | PRSS1ACRTRPV1SMN1; SMN2MEN1 | |
| SCHEMBL6464036 | 0.88 | TRPV1 (0.41) | SRD5A1TRPV1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |